Antiseptics (Greek αντί, against, and σηπςις, rotting) are antimicrobial substances that are applied to living tissue/skin to reduce the possibility of infection, sepsis, or putrefaction. They should generally be distinguished from antibiotics that destroy microorganisms within the body, and from disinfectants, which destroy microorganisms found on non-living objects. Some antiseptics are true germicides, capable of destroying microbes (bacteriocidal), whilst others are bacteriostatic and only prevent or inhibit their growth. Antibacterials are antiseptics that only act against bacteria.
How it works[]
For the growth of bacteria there must be a certain food supply, moisture, in most cases oxygen, and a certain minimum temperature (see bacteriology). These conditions have been specially studied and applied in connection with the preserving of food and in the ancient practice of embalming the dead, which is the earliest illustration of the systematic use of antiseptics.
In early inquiries a great point was made of the prevention of putrefaction, and work was done in the way of finding how much of an agent must be added to a given solution, in order that the bacteria accidentally present might not develop. But for various reasons this was an inexact method, and today an antiseptic is judged by its effects on pure cultures of definite pathogenic cellular single helix microbes, and on their vegetative and spore forms. Their standardization has been affected in many instances, and a water solution of phenol of a certain fixed strength is now taken as the standard with which other antiseptics are compared.