House, M.D. - Season Two was released by Universal on DVD on August 22, 2006.
In addition to the 24 episodes from season two, it contains
- "An Evening With House" panel discussion at the Academy of Television Arts & Sciences with the cast and executive producers
- Commentary by executive producers David Shore and Katie Jacobs on the episodes "Autopsy" and "No Reason"
- Alternate takes from the episodes "Daddy's Boy" and "Sleeping Dogs Lie" with Lisa Edelstein (Cuddy) and Jennifer Morrison (Cameron) performing, like, Valley Girl style
- "It Could Be Lupus..." montage of clips highlighting the show's most common diagnosis
- Blooper Reel
- Subtitles in English and Spanish
- Dolby Digital 5.1 audio track
Season 2: 2005-2006
Episode Name (original air date)
- Acceptance (September 13, 2005)
- Autopsy (September 20, 2005)
- Humpty Dumpty (September 27, 2005)
- TB or Not TB (November 1, 2005)
- Daddy's Boy (November 8, 2005)
- Spin (November 15, 2005)
- Hunting (November 22, 2005)
- The Mistake (November 29, 2005)
- Deception (December 13, 2005)
- Failure to Communicate (January 10, 2006)
- Need to Know (February 7, 2006)
- Distractions (February 14, 2006)
- Skin Deep (February 20, 2006)
- Sex Kills (March 7, 2006)
- Clueless (March 28, 2006)
- Safe (April 4, 2006)
- All In (April 11, 2006)
- Sleeping Dogs Lie (April 18, 2006)
- House vs. God (April 25, 2006)
- Euphoria (Part 1) (May 2, 2006)
- Euphoria (Part 2) (May 3, 2006)
- Forever (May 9, 2006)
- Who's Your Daddy? (May 16, 2006)
- No Reason (May 23, 2006)
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