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About House, M.D.

House, also known as House, M.D., was a critically-acclaimed American medical drama television series created by David Shore and executively produced by film director Bryan Singer. The Emmy and Peabody award-winning medical drama debuted on the FOX Network on November 16, 2004, and aired its last episode on May 21, 2012.

For eight years the show brought in people from around the globe, bringing intrigue and mystery in the form of unusual medical cases in a vein reminiscent of the mysteries solved by Sherlock Holmes. Furthermore, these cases were the catalyst for the discussion of philosophical and ethical issues and decisions, a lot of which were not left with a clear victor, but all of which revealed more and more of the character of each of the different doctors that comprised the team each year. In the end, while the team didn't completely understand (or appreciate) House's methods fully, the show gives a final hurrah as each of the members walks away with something they realize was the right thing to do after all. Although the mantra "Everybody Lies" is proven over and over again, the concept that "people never change, they only come up with better lies" is tested up until the last moments as the characters (and the show) drive off into an adventure left to the imagination.

Everything is challenged, nothing is sacred, and the most profound revelations of life can be found within the 172 hours of television given over the course of the eight seasons of pill-popping, dripping sarcasm, dark humor, and intelligent storytelling ever to grace the small screen of the living room (or large screen, if that may be the case, but then...everybody lies). This wiki is intended for your perusal to catch up, read, make new or more complete connections on the various subject matter, or perhaps relive the funny if outrageous times given to us by actor Hugh Laurie and company.

Enjoy!

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Muscle death

Muscle death or myopathy, a form of necrosis, is the result of a lack of blood to a muscle resulting in the muscle eventually ceasing to become a living cell. As dead tissue, the muscle then starts to rot, causing gangrene, poisoning the bloodstream and eventually resulting in the death of the patient unless the dead muscle is removed. Several things can cause muscle death, such as a lack of blood due to an infarction or a severe infection such as Necrotizing fasciitis. It is most commmonly seen in severe frostbites.

If the underlying cause is treated before too much muscle dies, the body will be able to process the dead tissue through the liver. However, if it becomes too widespread, amputation is the only sure method of preventing the death of the patient. Otherwise, the dead muscle tissue will overwhelm the body's other organs, particularly the liver.


Fortunately, muscle death is very rare, but its symptoms are not unique to the condition. As a result, it is difficult to diagnose.

Gregory House suffered from muscle death after his infarction. Instead of agreeing to amputation, he attempted to treat the condition by having the arteries that fed the muscle bypass it, restoring circulation to still living tissue while slowing the entry of dead tissue into the blood stream, hoping that the muscle would heal and allow him the use of most of his leg. However, the procedure was very painful during the recovery period and he agreed to be put into an induced coma. During his coma, his medical proxy, his girlfriend Stacy, instead had the dead muscle removed entirely.

The delay in diagnosis and the removal of the muscle both weakened House's right leg and left him with chronic pain. It also cost him his relationship with Stacy.

In medicine, myopathy is a disease of the muscle in which the muscle fibers do not function properly. This results in muscular weakness. Myopathy means muscle disease (Greek : myo- muscle + patheia : suffering). This meaning implies that the primary defect is within the muscle, as opposed to the nerves ("neuropathies" or "neurogenic" disorders) or elsewhere (e.g., the brain). Muscle cramps, stiffness, and spasm can also be associated with myopathy.

Muscular disease can be classified as neuromuscular or musculoskeletal in nature. Some conditions, such as myositis, can be considered both neuromuscular and musculoskeletal.

Signs and symptoms

Common symptoms include muscle weakness, cramps, stiffness, and tetany.

Systemic diseases

Myopathies in systemic disease results from several different disease processes including endocrine, inflammatory, paraneoplastic, infectious, drug- and toxin-induced, critical illness myopathy, metabolic, collagen related, and myopathies with other systemic disorders. Patients with systemic myopathies often present acutely or sub acutely. On the other hand, familial myopathies or dystrophies generally present in a chronic fashion with exceptions of metabolic myopathies where symptoms on occasion can be precipitated acutely. Most of the inflammatory myopathies can have a chance association with malignant lesion; the incidence appears to be specifically increased only in patients with dermatomyositis.

There are many types of myopathy.


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House: "Is this hell? An eternity of people trying to convince me to live?"
Cameron: "Who says I'm here to convince you to live?"
―Cameron's hallucination appears in Everybody Dies
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May 2021 Featured Article

The feature article for May, 2021 will be Sex Kills

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April 2021 Featured Article

Next month's featured article will be Muscle death

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March 2021 featured article

Once again, thank you for your patience while I got this month's featured article up and running. For next month, I've gone with Season 8's Perils of…

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February 2021 featured article

Thank you for waiting a week while I got around to posting the featured article for January. Next month's featured article will be another patient , …

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