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About House, M.D.

House, also known as House, M.D., was a critically-acclaimed American medical drama television series created by David Shore and executively produced by film director Bryan Singer. The Emmy and Peabody award-winning medical drama debuted on the FOX Network on November 16, 2004, and aired its last episode on May 21, 2012.

For eight years the show brought in people from around the globe, bringing intrigue and mystery in the form of unusual medical cases in a vein reminiscent of the mysteries solved by Sherlock Holmes. Furthermore, these cases were the catalyst for the discussion of philosophical and ethical issues and decisions, a lot of which were not left with a clear victor, but all of which revealed more and more of the character of each of the different doctors that comprised the team each year. In the end, while the team didn't completely understand (or appreciate) House's methods fully, the show gives a final hurrah as each of the members walks away with something they realize was the right thing to do after all. Although the mantra "Everybody Lies" is proven over and over again, the concept that "people never change, they only come up with better lies" is tested up until the last moments as the characters (and the show) drive off into an adventure left to the imagination.

Everything is challenged, nothing is sacred, and the most profound revelations of life can be found within the 172 hours of television given over the course of the eight seasons of pill-popping, dripping sarcasm, dark humor, and intelligent storytelling ever to grace the small screen of the living room (or large screen, if that may be the case, but then...everybody lies). This wiki is intended for your perusal to catch up, read, make new or more complete connections on various subject matter, or perhaps relive the funny if outrageous times given to us by actor Hugh Laurie and company.

Enjoy!

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Differential diagnosis

In medicine, a differential diagnosis is the distinguishing of a particular disease or condition from others that present similar clinical features. Differential diagnostic procedures are used by physicians and other trained medical professionals to diagnose the specific disease in a patient, or, at least, to eliminate any imminently life-threatening conditions. Often, each individual option of a possible disease is called a differential diagnosis (e.g. acute bronchitis could be a differential diagnosis in the evaluation of a cough, even if the final diagnosis is common cold).

More generally, a differential diagnostic procedure is a systematic diagnostic method used to identify the presence of a disease entity where multiple alternatives are possible. This method is essentially a process of elimination or at least a process of obtaining information that shrinks the "probabilities" of candidate conditions to negligible levels, by using evidence such as symptoms, patient history, and medical knowledge to adjust epistemic confidences in the mind of the diagnostician (or, for computerized or computer-assisted diagnosis, the software of the system).

Differential diagnosis can be regarded as implementing aspects of the hypothetico-deductive method, in the sense that the potential presence of candidate diseases or conditions can be viewed as hypotheses that physicians further determine as being true or false.

Common abbreviations of the term "differential diagnosis" include DDx, ddx, DD, D/Dx, ΔΔ, or ΔΔ𝛘.

A differential diagnosis is also commonly used within the field of psychiatry/psychology, where two different diagnoses can be attached to a patient who is exhibiting symptoms which could fit into either diagnosis. For example, a patient who has been diagnosed with bipolar disorder may also be given a differential diagnosis of borderline personality disorder, given the similarity in the symptoms of both conditions.

Strategies used in preparing a differential diagnosis list vary with experience of the healthcare provider. While novice providers may work systemically to assess all possible explanations for a patients concerns, those with more experience often draw on clinical experience and pattern recognition to protect the patient from delays, risks, and cost of inefficient strategies or tests. Effective providers utilize an evidence-based approach, complementing their clinical experience with knowledge from clinical research.

Depending on the situation, the possible conditions may be prioritized in a different manner. If the patient is seriously ill, a differential will generally be prioritized by urgency - which conditions have to be treated immediately. In less serious cases, a differential will be prioritized by the likelihood of each possible diagnosis.That being said, physicians have to keep in mind that very dangerous conditions can present with prosaic symptoms. For example, a ruptured aortic aneurysm may only present with back pain.

General components

A standard of care differential diagnosis has four steps. Patient safety requires that the physician:

  1. Gathers all information about the patient and creates a symptoms list. The list can be in writing or in the physician's head, as long as they make a list.
  2. Lists all possible causes (candidate conditions) for the symptoms. Again, this can be in writing or in the physician's head but it must be done.
  3. Prioritizes the list by placing the most urgently dangerous possible causes at the top of the list.
  4. Rules out or treats possible causes, beginning with the most urgently dangerous condition and working down the list. Rule out—practically—means use tests and other scientific methods to determine that a candidate condition has a clinically negligible probability of being the cause.

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Current Featured Quote

House: "Is this hell? An eternity of people trying to convince me to live?"
Cameron: "Who says I'm here to convince you to live?"
―Cameron's hallucination appears in Everybody Dies
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  • SteveHFisyh

    Sorry I'm very late this month everyone, but I finally picked the featured article for April - Family. Please help us improve it to featured status!SteveHFisyh (talk) 01:32, March 15, 2019 (UTC)

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  • SteveHFisyh

    No-one got back to me by deadline, so after fliipping through a few articles I found one that probably should have been featured a long time ago, even though we've done a related article: Differentia…

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  • SteveHFisyh

    Many thanks to Voxhumana42, both for her contributions to the Wiki last month, and for chosing next month's featured article Headache. Please help us improve it to featured article status. SteveHFisy…

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  • SteveHFisyh

    Thank you very much to Diegogonzalez05 for both his contributions last month and his choice of next month's featured article - Sepsis. Frankly, given its importance as a condition on the show (three …

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