Foley has been acting since 1991, when she made an appearance on the series Sessions. Although she has mostly worked in supporting roles, she appeared as Christie Parker in 17 episodes of Once and Again in 2001. As March 2012, she has appeared in sixteen episodes of House.
Foley is the daughter of actor/comedian Billy Crystal and is married to Michael Foley, whom she met while she was attending Northwestern University in the early 1990s. She has one daughter, Ella, who was born in 2003.
- Appeared with Joe Morton on Eureka
- Appeared with Candice Bergen in Bride Wars
- Appeared with Nestor Carbonell and Sherilyn Fenn on Century City
- Appeared with Andrew Keegan, Sunny Mabrey and Keri Lynn Pratt in A Midsummer Night's Rave
- Appeared with Sela Ward and Marin Hinkle on Once and Again
- Appeared with Peter Jacobson and Michael Nouri in 61*
- Appeared with Mos Def on NYPD Blue
- Appeared with Samantha Mathis and Joshua Malina in The American President
- Appeared with David Strathairn in Losing Isaiah
- Appeared with Pruitt Taylor Vince in City Slickers II: The Legend of Curly's Gold