Like cast mates Topher Grace, Ashton Kutcher and Mila Kunis, who also made their debut on That 70s Show, Prepon used her first acting job as a springboard to larger things. She has had featured roles in Slackers, Romancing The Bride, Karla (as the notorious accomplice to Paul Bernardo, Karla Homolka), October Road, and How I Met Your Mother.
Prepon's latest project is playing Alex Vause on Orange is the New Black; a Netflix series about women in prison and the life that they live
Prepon's natural hair color is red, but she has been dying it blond for several years.
- Appeared with Jake McDorman in Are You There, Chelsea?
- Appeared with Greg Grunberg and Michelle Trachtenberg on Love Bites
- Appeared with Anne Dudek and Charlene Amoia on How I Met Your Mother
- Appeared with Jake Weber on Medium
- Appeared with Todd Louiso on In Plain Sight
- Appeared with Evan Jones and Odette Annable on October Road
- Appeared in That 70s Show with Kurtwood Smith.
- Appeared with Patrick Bauchau in Karla
- Appeared with Breckin Meyer on King of the Hill
- Appeared with Lucas Till in Lightning Bug