Leighton made her first major acting appearance on an episode of Law & Order in 1999. Since then, she has run up a respectable list of credits, including appearance on several episodes of 24 and Surface.
Leighton is currently starring as the character Blair Waldorf in Gossip Girl. Look forward to seeing her at the movies in Killer Movie in 2008.
Meester appeared in 2011 in the film The Oranges. Elements of the plot of the film echo her role on House as she plays a young woman who an older man played by Hugh Laurie falls in love with.
- Appeared with Hugh Laurie in The Oranges
- Appeared with Ron Livingston in Going the Distance
- Appeared with Jimmi Simpson in Date Night
- Appeared with Beau Garrett on Entourage
- Appeared with Nestor Carbonell in Killer Movie
- Appeared with Lyndsy Fonseca in The Beautiful Ordinary
- Appeared with George Wyner on Shark
- Appeared with Nicholas D'Agosto in Drive Thru
- Appeared with Nicholas D'Agosto in Inside
- Appeared with Jennifer Morrison and Jesse Spencer in Flourish