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Melissa is the ex-wife of Tucker, the patient in the Season 6 episode Wilson. She is the mother of Emily. She was portrayed by actress Katherine LaNasa.

When Wilson calls Emily to try to convince her to come and see her estranged father, Emily comes, but brings Melissa as well. Tucker is pleased they both showed up even though his new girlfriend Ashley is there.  

When Tucker gets sicker, he makes Melissa his medical proxy. When Tucker grows closer to death, he also grows closer to Melissa. However, when he recovers, he decides to go back to Ashley. 

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