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- "You’re orange, you moron! It’s one thing for you not to notice, but if your wife hasn’t picked up on the fact that her husband has changed color, she’s just not paying attention. By the way, do you consume just a ridiculous amount of carrots and mega-dose vitamins?"
- ―House's diagnostic method
The Orange Man was a clinic patient in the Pilot episode. He came in complaining of a sore back, but failed to notice that his skin was a bright orange color. He was apparently an important donor to the hospital because he got an audience with Lisa Cuddy to complain about House. He was portrayed by actor Andrew Airlie.
Orange Man was House's first clinic patient after returning to the clinic after a refusal to do clinic duty for six years. Orange Man came into the clinic claiming that his back had become sore while he was golfing. House gave him a Vicodin for the pain. House told him that he was orange and apparently he had not noticed. House also told him that his wife is having an affair because it was one thing that he hadn't noticed that he was orange, but if his wife hadn't noticed than she must not have been paying any attention to him.
House diagnoses the orange skin as being caused by eating too many carrots turning him yellow (due to excess of carotene, a natural dietary pigment), along with Niacin (Vitamin B3) turning him red.
He came back to the hospital once more to complain to Lisa Cuddy about House's behavior. It appears that he and his wife had had a falling out because he no longer had the ring on his finger that (or he's taken the ring off to see if his wife is really ignoring him as much as House says). Cuddy was sympathetic but refused to discipline House as he was "the best doctor we've got".