The second season of House premiered on September 13, 2005 and ended on May 23, 2006.
During the season, House tries to cope with his feelings for his ex-girlfriend Stacy Warner, who, after House diagnosed her husband with Acute intermittent porphyria, has taken a job in the legal department of the PPTH.
Other major storylines for this season include Cameron's risky behaviour after being possibly exposed to HIV and her relationship with Chase, Foreman about to die and his rivalry with Cameron, Chase's father dying and its consequences to both Chase and House since it led to the death of a patient and Cuddy's desire to be a mother.
Sela Ward's chemistry with Laurie in the final two episodes of season one was strong enough to have her character return in seven episodes of the second season.
The season gained high Nielsen ratings; "No Reason" was watched by 25.47 million viewers, the show's biggest audience ever at that point. Season two averaged 17.3 million viewers an episode, outperforming season one by 30%. The number of viewers made it the tenth most-watched show of the 2005–2006 television season.
Writer Lawrence Kaplow won a Writers Guild of America Award in 2006 for the episode "Autopsy".
Season 2 of House M.D. returned to television in September 2005, and contained 24 episodes. House, M.D. - Season Two was initially released to DVD on August 22, 2006.
Season 2 largely followed the pattern of Season 1 with one big twist. To humanize its protagonist, the series delves deeper into the past of Gregory House by making him continue to face his past with the one true love of his life to that point, Stacy Warner. We find out the ultimate loner longs for the connection he had with this woman. He makes the transition from a juvenile personality who is obsessed with getting Stacy just to admit she’s still in love with him to a hurt adult who realizes that she’s much better off without him. Unlike Lisa Cuddy in Season 7, Stacy realizes House is right just at the moment when it appears that their relationship appears to once again become permanent. However, no matter how noble House’s motives when he lets Stacy return to her husband Mark, it’s clear both that the second separation is having a tremendous effect on him and that he’s never going to admit it to himself.
The other characters start to develop as well. When Allison Cameron treats a party boy she experiments with Ecstacy and with Robert Chase, but immediately regrets both. Meanwhile, we learn more about the atrophied personal life of Eric Foreman where he faces the choice of either death or permanent brain damage when he catches a disease from a patient and decides to reconnect with his father. We also get a much deeper insight into House himself when his parents John House and Blythe House drop by the hospital for a visit. We also see House finding it difficult to be his usual self when Eric Foreman is ill. Cuddy’s sick handyman exposes her inability to be objective with people she cares about - a pattern that continues in several cases throughout the series.
Stacy Warner returns to PPTH, having been officially hired as the hospital’s General Counsel. House eventually realizes that he still has feelings for her. In an attempt to prove that she feels the same way about him, he breaks into her therapist’s office and reads her file. House learns that she is not sleeping with her husband Mark Warner. He tries to get back with her by killing a rat that has invaded her home, but soon changes his mind after learning that the rat has an illness that brings out the diagnostician in him.
House cures the rat after capturing him and keeps him as a pet. Stacy soon realizes that he's read her file and gets mad at him. House soon gets in legal trouble over his medical billings and they fly to Baltimore together. But due to a huge snowstorm, their plane is delayed and while in the airport, they share a kiss.
Soon afterward, House sleeps with Stacy. Meanwhile Mark confronts House because he thinks that he is losing Stacy. Stacy tells House that she is going to break up with Mark and be with House once again. But House, knowing that history is likely to repeat itself again tells her to stay with him. Stacy quits her job and leaves the hospital for good along with Mark..
With his ex gone, House's leg pain greatly increases and Wilson hopes that it means nerve regeneration, but really it is because he misses Stacy. A doctor that caught House cheating on a test nearly twenty years ago comes to the hospital to give a speech regarding a new drug. House soon exacts revenge on him by bringing the effectiveness of his “breakthrough“ into question.
James Wilson gets a divorce from his third wife and he moves in with House. He has trouble with it at first but eventually gets used to it. He gets mad at House because he didn't invite him to his weekly poker game but soon all is forgiven after House realizes that Wilson is living with one of his patients.
Cuddy's handyman falls off her roof. Cuddy attempts to work with House and his team to help him but she finds House is ahead of her at every turn even though he could care less about the patient. She realizes that she hasn't been a real doctor in years. She decides that she wants a baby and considers Wilson as sperm donor. She invites him over until dinner when he begins to think that she has cancer and she never gets the courage to ask him.
In the two-part episode Euphoria, the team face a huge crisis on their hands when Foreman is accidentally infected with a disease that has already killed one patient. He nearly dies from it but House, Cameron, and Chase manage to save his life. It soon becomes clear that it takes some time for Foreman to recover from his near-death experience.
When Chase kisses a 9-year old cancer patient who asks him because she wants to be kissed before the disease takes her life, House taunts him about it while simultaneously admiring the patient‘s ability to manipulate Chase. In the meantime, Chase learns of his father's death from lung cancer, which came as a complete surprise to him. Distracted, Chase ends up accidentally killing a patient. He tells Kayla's brother Sam McGinley that he had a hangover leading him to sue Chase and the entire hospital for damages amounting to ten million dollars. Stacy helps him prepare for the disciplinary hearing and soon, no permanent charges are pressed against him although Chase gets a week's suspension and Foreman becomes Head of Diagnostics. House later figures out that Chase has been working extra time in the ER because his father disinherited him.
When Foreman is put in charge of diagnostics. House makes him miserable, but as the administrative work is getting done, Cuddy hints the position as head of diagnostics could be made permanent. However, House manages to save a patient having HIV that Foreman wanted to discharge, so Cuddy withdraws the offer, with both of them realizing that House will soon be back in charge. Foreman remains head of the department for a few more weeks until at the middle of the episode Deception when Foreman‘s time literally runs out.
Another patient with HIV accidentally coughs blood into Cameron's face and mouth. Unable to cope with the fact that she might have HIV, she borrows some Ecstacy and sleeps with Chase. Thankfully, she soon learns that her HIV tests were negative and that sleeping with Chase and taking Ecstacy were big mistakes.
At the end of the season, House is shot and gravely injured by a disgruntled former patient's husband. It's soon shown that the events involving his fighting with Wilson and talking to his team never actually happened as they were in fact hallucinations. The season ends on a cliffhanger as House is seen being wheeled into the ER by his team and he makes a request for ketamine before losing consciousnesses altogether.
- Hugh Laurie as Dr. Gregory House (24/24)
- Lisa Edelstein as Dr. Lisa Cuddy (24/24)
- Omar Epps as Dr. Eric Foreman (24/24)
- Robert Sean Leonard as Dr. James Wilson (24/24)
- Jennifer Morrison as Dr. Allison Cameron (24/24)
- Jesse Spencer as Dr. Robert Chase (24/24)
- Sela Ward as Stacy Warner (7/24) (episodes 1, 3, 6-8, 10-11)
- Stephanie Venditto as Nurse Brenda Previn (4/24) (episodes 2, 8, 12-13)
- Currie Graham as Mark Warner (3/24) (episodes 6, 7, 11)
Notable Guest Stars
- R. Lee Ermey as John House (1/24)
- Diane Baker as Blythe House (1/24)
- Charles S. Dutton as Rodney Foreman (1/24)
- LL Cool J as Clarence
- Sasha Pieterse as Andie
- Cynthia Nixon as Anica Jovanovich
- Michael O'Keefe as Fletcher Stone
- Mimi Kennedy as Greta
- Julie Warner as Margo Dalton
- Elle Fanning as Stella Dalton
- Dan Butler as Philip Weber
- Cameron Richardson as Alex
- Howard Hesseman as Henry Errington
- Michelle Trachtenberg as Melinda Bardach
- William Katt as Walter
- Scott Michael Campbell as Joe Luria
- D.B. Sweeney as Dylan Crandall
- Elias Koteas as Jack Moriarty
- Stacy Warner starts working at the hospital. House plans to make her admit that she still cares for him.
- House’s parents come for a visit during a layover on a flight that passes through Newark. House unsuccessfully tries to dodge the meeting.
- Cameron is exposed to HIV. She later tests negative.
- Cameron tries Ecstasy and, under its influence, sleeps with Chase.
- Distracted by his father’s death, Chase makes a mistake that costs a patient her liver and then her life. He’s suspended for a week as a result, but House is put under the supervision of Foreman, as punishment for House's failure to properly supervise Chase.
- House goes to Baltimore with Stacy to work out some issues with his billings. When they’re stranded by a snowstorm, they share a brief kiss, but it goes no further because they’re interrupted by a case.
- House and Stacy sleep together, and she considers leaving Mark. House initially tells her she has to leave Mark to be with him, but later realizes that Mark makes Stacy happier than he ever could. Stacy leaves the hospital.
- House’s leg pain grows worse. Wilson blames his break-up with Stacy.
- House gets revenge on the doctor who ratted him out for cheating in medical school.
- House finally solves a 12 year old case when a young boy comes to the hospital with identical symptoms.
- House and God battle to a tie over a case involving a teenage preacher.
- Foreman nearly dies when he’s exposed to an illness that kills the original patient. He suffers temporary brain damage as a result. He also reconnects with his father, whom he hasn’t seen in person in eight years.
- We learn Foreman’s mother is suffering from dementia, most likely due to Alzheimer's disease.
- House is shot and has hallucinations that make him believe his assailant is in the ICU bed right next to him. The assailant is never identified or apprehended.
|Image||Title||Original Airdate||U.S. Viewers|
|1. "Acceptance"||September 13, 2005||15.91|
Plot: When a death row inmate takes ill, House tricks Stacy into getting him released to the hospital so he can figure out what is wrong with him. When the prisoner improves, Cuddy tries to get rid of him, only to have more serious symptoms appear. Meanwhile, Cameron deals with a clinic patient’s terminal diagnosis by trying to prove everyone wrong, and when the diagnosis seems to be confirmed at each step, she gets more and more desperate to save her patient while wondering why House only cares about a murderer.
|2. "Autopsy"||September 20, 2005||13.64|
Plot: A nine year old with terminal cancer who is hallucinating comes to the hospital. House thinks her bravery in the face of imminent death is actually a symptom of her condition. Meanwhile, House tries to get over a cold and test drives a motorcycle.
|3. "Humpty Dumpty"||September 27, 2005||13.37|
Plot: Cuddy’s handyman Alfredo falls off the roof while repairing it. However, apart from the normal trauma, he appears to develop other very serious symptoms. Cuddy puts herself on the case, but her lack of objectivity and her concern about the patient being able to maintain his livelihood makes House confront her about the proper course of treatment. Meanwhile, Cameron quizzes Cuddy about why House is still working for her, and Chase asks House about his history with Cuddy. Finally, Foreman has a rather difficult problem with a patient who believes the doctors are trying to stick him with inferior medication.
|4. "TB or Not TB"||November 1, 2005||12.18|
Plot: House treats a famous tuberculosis doctor who has diagnosed himself with TB. However, the constellation of symptoms convinces House there’s a more serious underlying condition. When it turns out the patient does have tuberculosis, his conscience forces him to refuse treatment for it and House has to convince him that tuberculosis isn’t the problem, but they will never known unless he agrees to be treated for it. Meanwhile, a comedy of errors occurs in the clinic when a patient who believes she has cancer is seen by Dr. Foreman wearing Dr. House’s name-tag in order to cover for House. When she demands an apology for the way “House” has treated her, it becomes clear to House and Foreman that the only reason Cuddy’s even considering demanding an apology is not because of Foreman’s behavior, but her perception that House always crosses the line. In the end, House finds a way to make it look like he has apologized to satisfy Cuddy.
|5. "Daddy's Boy"||November 8, 2005||14.15|
Plot: A twenty two year old who is having the sensation of being severely shocked has a strained relationship with his father which makes it hard for the team to diagnose him. Meanwhile, House tries to avoid a dinner with his father and mother.
|6. "Spin"||November 15, 2005||12.95|
Plot: A famous cyclist who admits to blood doping becomes House patient and Cameron wants to report him for cheating. Meanwhile, House attempts to force Stacy to admit how she feels for him by going to disrupt Mark Warner’s therapy group and by stealing Stacy's files from her therapist to get more insight.
|7. "Hunting"||November 22, 2005||14.72|
Plot: A man with full blown AIDS follows House home and demands to be treated by him. When House agrees, his condition continues to deteriorate, but the answer may be in his father. Meanwhile, Stacy needs House's help to capture a rat which becomes House's pet Steve McQueen.
|8. "The Mistake"||November 29, 2005||14.91|
Plot: Stacy prepares Chase and House for a disciplinary case where a simple mistake by Chase eventually results in the death of the patient. When the hospital is sued over the incident, Stacy has to dig for the truth both to save the hospital and Chase’s career. However, she’s distracted by her ongoing feud with House over his review of her confidential therapy records.
|9. "Deception"||December 13, 2005||14.52|
Plot: When an off-track gambler comes to the hospital, the team quickly diagnoses her with Munchausen's syndrome, but House thinks that there may be more fact than fiction to the woman's story. Meanwhile, House takes advantage of being supervised by Foreman.
|10. "Failure to Communicate"||January 10, 2006||14.83|
Plot: A famous writer finds himself literally at a loss for words when he starts suffering from aphasia. Meanwhile, House and Stacy are stranded in Baltimore and they share a kiss.
|11. "Need to Know"||February 7, 2006||22.24|
Plot: A women with muscle spasms comes to the hospital. As the team looks into the patient‘s life, the only diagnosis that makes sense is one the patient insists on denying. Meanwhile, Wilson wants House and Stacy to confront their feelings for each other, Cameron refuses to get the results of her HIV test and House is no longer under the supervision of Foreman.
|12. "Distractions"||February 14, 2006||19.20|
Plot: A severe burn victim becomes House's patient when he develops tachycardia, but because of his conditions, they can‘t use most of their usual testing procedures. Meanwhile, House plots revenge on a doctor that he went to medical school with by trying to prove that a new migraine prevention medication doesn't work.
|13. "Skin Deep"||February 20, 2006||14.18|
Plot: A model with a heroin addiction collapses on the catwalk. Meanwhile, House's leg pain worsens because he misses Stacy.
|14. "Sex Kills"||March 7, 2006||20.56|
Plot: House quickly diagnoses a life threatening illness, but it won't do the patient much good unless he can figure out what was causing an illness in an accident victim whose heart the living patient needs for a transplant. Meanwhile, House suspects Wilson of cheating on his wife.
|15. "Clueless"||March 28, 2006||21.44|
Plot: A man who started having trouble breathing while role playing with his wife is quickly diagnosed with Lupus by the team, but House thinks that the wife may be poisoning him. Meanwhile, House and Wilson discuss the terms of their new living arrangements.
|16. "Safe"||April 4, 2006||22.71|
Plot: Melinda, a young immunocompromised heart transplant recipient, goes into anaphylactic shock in her home clean room. The team has to deal with her increasingly severe symptoms and her wish to rebel against her mother’s over protectiveness. Meanwhile,the relationship between House and Wilson becomes increasingly strained as Wilson continues to live with House after separating from his wife.
|17. "All In"||April 11, 2006||21.20|
Plot: A young boy seems to have the same symptoms as one of House's old patients who ended up dying, and the team attempts to find out what killed her in time to save him. Meanwhile, House tries to keep Cuddy away from him by helping Wilson during poker night.
|18. "Sleeping Dogs Lie"||April 18, 2006||22.64|
Plot: A woman with a life threatening case of insomnia comes to the hospital after swallowing a whole bottle of sleeping pills. The team soon learn that she is planning on leaving her girlfriend, Max. When her liver fails Max offers to donate hers and the team are faced with an ethical dilemma. Meanwhile, Cameron accuses Foreman of plagiarism because they both wrote an article about the same patient.
|19. "House vs. God"||April 25, 2006||24.52|
Plot: House wants to call a 15-year-old faith healer's bluff, but when the boy is admitted into the hospital he seemingly causes a cancer patient's condition to go into remission. After being diagnosed, the boy refuses brain surgery, but when his condition worsens, House and his staff have to make a decision.
|20. "Euphoria (Part 1)"||May 2, 2006||22.71|
Plot: A police officer is admitted with symptoms of unbelievable happiness. However, his behavior starts changing as he gets sicker and sicker, when suddenly one of the team starts exhibiting inappropriate happiness as well.
|21. "Euphoria (Part 2)"||May 3, 2006||17.16|
Plot: After their previous patient dies, the rest of the team rushes to diagnose what is wrong with Foreman and realize that the disease is progressing faster in him than in the deceased patient. Meanwhile, Cuddy refuses to authorize an autopsy on the previous patient on the grounds that whatever he had may spread through the hospital.
|22. "Forever"||May 9, 2006||24.29|
Plot: The team is faced with a woman whose behavior appears to be a threat to her newborn son. Meanwhile, Foreman starts to recover from his near fatal illness.
|23. "Who's Your Daddy?"||May 16, 2006||22.38|
Plot: An old friend of House shows up with his newly found daughter, who has survived Hurricane Katrina. House agrees to take the case only to try to convince his friend that the young woman is lying to him.
|24. "No Reason"||May 23, 2006||25.47|
Plot: After a former patient shoots House, House awakens to find the shooter in the next bed. He also finds that he’s been given an experimental treatment that has eliminated his leg pain, but may have also affected his mind. Meanwhile, the team tries to treat a patient whose test results keep coming up negative even as his bizarre array of symptoms continue to get worse. As the shooter continues to confront him about his seemingly diminishing mental skills and lack of humility, House figures that something is seriously wrong and that must solve the puzzle posed by the other patient in order to get things back to normal.
|June 2011||July 2011||August 2011|
|Season 7||Season 2||Martha M. Masters|